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Venlafaxine uses and side effects

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Introduction

Venlafaxine is an antidepressant medicine that belongs to the class of SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors). It works by increasing the levels of serotonin and norepinephrine in the brain, which helps improve mood, reduce anxiety, and relieve depressive symptoms.


Composition

The main active ingredient is:

  • Venlafaxine Hydrochloride

Formulations:

  • Immediate-release tablets
  • Extended-release (XR/ER) capsules or tablets

Inactive ingredients vary by manufacturer and may include lactose, cellulose, magnesium stearate, gelatin (in capsules), etc.


Uses

Venlafaxine is commonly prescribed for:

  1. Major Depressive Disorder (MDD)
  2. Generalized Anxiety Disorder (GAD)
  3. Panic Disorder
  4. Social Anxiety Disorder
  5. Sometimes off-label for nerve pain or hot flashes in menopause

Side Effects

Common side effects:

  • Nausea, vomiting
  • Dizziness or headache
  • Dry mouth
  • Sweating
  • Insomnia or drowsiness
  • Constipation or loss of appetite

Serious side effects (need urgent medical attention):

  • High blood pressure
  • Increased heart rate
  • Severe mood changes (agitation, suicidal thoughts)
  • Serotonin syndrome (confusion, fever, muscle stiffness, seizures)
  • Withdrawal symptoms if stopped suddenly (dizziness, irritability, electric-shock sensations)

Important Note: Venlafaxine should never be stopped suddenly—dosage must be reduced gradually under a doctor’s supervision.


Brand Names of Venlafaxine

Some commonly available brand names include:

  • Effexor / Effexor XR
  • Venlift
  • Favenza
  • Viepax
  • Venax
  • Velaxin
CategoryDetails
IntroductionVenlafaxine is an antidepressant of the SNRI (Serotonin-Norepinephrine Reuptake Inhibitor) class. It helps balance brain chemicals (serotonin & norepinephrine) to improve mood and reduce anxiety.
Active IngredientVenlafaxine Hydrochloride
FormulationsImmediate-release tablets Extended-release (XR/ER) capsules or tablets
Uses1. Major Depressive Disorder (MDD) 2. Generalized Anxiety Disorder (GAD) 3. Panic Disorder 4. Social Anxiety Disorder 5. Off-label: nerve pain, menopausal hot flashes
Common Side EffectsNausea, vomiting, headache, dizziness, sweating, dry mouth, insomnia or drowsiness, constipation, loss of appetite
Serious Side EffectsHigh blood pressure, fast heart rate, severe mood changes (suicidal thoughts), serotonin syndrome, withdrawal symptoms if stopped suddenly
Important NoteNever stop suddenly — taper dose gradually under medical supervision.
Brand NamesEffexor / Effexor XR Venlift Favenza Viepax Venax Velaxin

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