Augmentin Uses and side effects
Table of Contents
📌 Introduction
- Augmentin is a widely used antibiotic.
- It belongs to the penicillin group, but with added protection against resistant bacteria.
- Manufactured under different brand names worldwide, including Augmentin in Pakistan.

🧪 Composition
- Amoxicillin (a broad-spectrum penicillin antibiotic)
- Clavulanic acid (a beta-lactamase inhibitor, prevents bacterial resistance to amoxicillin)
👉 Example: Augmentin 625 mg tablet usually contains:
- Amoxicillin 500 mg
- Clavulanic acid 125 mg
💊 Uses
Augmentin is prescribed for bacterial infections such as:
- Respiratory infections (sinusitis, pneumonia, tonsillitis, bronchitis)
- Ear, nose, and throat infections
- Skin and soft tissue infections (abscess, cellulitis)
- Urinary tract infections (UTIs)
- Dental infections
- Bone and joint infections
⚠️ Side Effects
Like all medicines, Augmentin may cause side effects:
Common:
- Diarrhea
- Nausea, vomiting
- Stomach upset / abdominal pain
- Mild skin rash
Less common but important:
- Allergic reactions (rash, itching, swelling, difficulty breathing → medical emergency)
- Liver problems (jaundice, abnormal liver function tests)
- Oral or vaginal thrush (fungal overgrowth due to antibiotic use)
- Rare: Severe skin reactions (Stevens–Johnson syndrome)
✅ Important Notes
- Always complete the full prescribed course, even if symptoms improve.
- Should be taken with food to reduce stomach upset.
- Avoid if you have penicillin allergy.
- Use with caution in liver or kidney disease.
Here’s a comparison table of Augmentin vs other commonly used antibiotics in Pakistan, covering their composition, coverage, uses, and side effects:
| Antibiotic | Composition | Coverage | Common Uses | Notable Side Effects |
|---|---|---|---|---|
| Augmentin (Amoxicillin + Clavulanic Acid) | Amoxicillin (penicillin) + Clavulanic acid (β-lactamase inhibitor) | Gram +, Gram –, some resistant bacteria | Respiratory infections, UTIs, skin infections, dental infections | Diarrhea, nausea, liver issues, allergic reactions |
| Amoxicillin | Amoxicillin only | Gram +, limited Gram – | Tonsillitis, otitis media, UTIs, mild respiratory infections | Allergy, rash, diarrhea |
| Cefixime (Suprax) | Third-generation cephalosporin | Strong Gram – (esp. typhoid, UTIs), some Gram + | Typhoid, UTIs, chest infections | Diarrhea, abdominal pain, rare allergies |
| Ceftriaxone (Rocephin) | Third-generation cephalosporin (injection) | Broad-spectrum Gram – and Gram + | Typhoid, pneumonia, meningitis, sepsis | Injection site pain, diarrhea, gallbladder issues |
| Azithromycin (Azomax) | Macrolide | Mainly Gram +, atypical bacteria | Typhoid, chest infections, STIs, throat infections | Stomach upset, prolonged QT interval (heart rhythm issue) |
| Ciprofloxacin | Fluoroquinolone | Gram – (esp. urinary & GI), less Gram + | UTIs, gastroenteritis, typhoid (resistance ↑) | Joint pain, tendon rupture (rare), dizziness |
| Levofloxacin | Fluoroquinolone | Gram + and Gram – (respiratory focus) | Pneumonia, UTIs, sinusitis, typhoid | GI upset, tendon damage (rare), CNS effects |
| Doxycycline | Tetracycline | Broad-spectrum | Acne, respiratory infections, malaria prevention | Photosensitivity (sunburn risk), stomach upset |
| Metronidazole (Flagyl) | Nitroimidazole | Anaerobic bacteria & protozoa | Dental infections, GI infections, gynecological infections | Metallic taste, nausea, alcohol intolerance reaction |
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